ProGsterol

ProGsterol is a peptide-based nutraceutical developed by Caregen to support glucose metabolism, lipid balance, and overall metabolic health. Its active ingredient, Deglusterol, is a proprietary peptide complex derived from Deobetide and Adiporin, designed to support key metabolic pathways associated with glucose regulation, insulin sensitivity, and fat metabolism. As a food supplement, ProGsterol is positioned as a science-based health nutrition solution for metabolic balance, particularly for individuals facing lifestyle-related metabolic challenges. It provides a practical non-invasive approach for early-stage metabolic management and long-term maintenance. ProGsterol completed the U.S. FDA New Dietary Ingredient (NDI) notification in March 2022, supporting its global regulatory positioning as a scientifically validated ingredient for metabolic health applications. <Clinical Highlights> - Clinical studies of Deglusterol demonstrated improvements across key metabolic parameters. In individuals with metabolic imbalance, supplementation reduced fasting blood glucose (up to -23 mg/dL), fasting insulin (up to -5.2 μU/mL), HOMA-IR (up to -2.3), and HbA1c (up to -0.9%), indicating improved glucose regulation. - In pre-diabetic populations, a 12-week study showed reductions in fasting blood glucose (-6.7 mg/dL), HbA1c (-0.3%), fasting insulin (-1.03 μU/mL), HOMA-IR (-0.43), and C-peptide (-0.12), supporting insulin sensitivity and early metabolic balance. - In individuals with metabolic syndrome and liver-related metabolic conditions, Deglusterol demonstrated reductions in liver fat grade and disease severity over a 3-month period, along with positive lipid metabolism changes. These results position ProGsterol as a metabolic wellness solution for pre-diabetic, metabolically imbalanced, and preventive health populations.