Gabapral® Stick Packs

Gabapral® is an innovative probiotic supplement based on Bifidobacterium adolescentis PRL2019, specifically developed to target the gut–brain axis in children with Irritable Bowel Syndrome (IBS) and recurrent abdominal pain. The strain is characterized by its ability to produce gamma-aminobutyric acid (GABA), a key neuromodulator involved in the regulation of visceral sensitivity and gut-brain communication. By colonizing the gut and activating specific metabolic pathways, PRL2019 has been shown to significantly increase GABA production within just a few days, contributing to the modulation of abdominal pain perception. Clinical evidence from randomized, placebo-controlled trials demonstrates a significant reduction in both the intensity and frequency of abdominal pain, along with an improvement in overall quality of life in pediatric IBS patients. Gabapral® represents a next-generation microbiome-based solution, leveraging a targeted mechanism of action to address a condition traditionally linked to the gut–brain axis. Gabapral® has been shortlisted at the NutraIngredients Awards Europe 2026 in the category “Product of the Year: Microbiome Modulation (in association with Probiota)”, further highlighting its innovation and relevance in the evolving microbiome space.